Cybec 400 Warnings

Based on Notification of the Ministry of Public Health: 1. Celecoxib is contraindicated in patients who are hypersensitive to this drug, in pregnant and lactating women.
2. Celecoxib is contraindicated in patients who have coronary artery surgery in the immediately postoperative period.
3. Celecoxib is contraindicated in patients with cardiovascular or cerebrovascular diseases.
4. If there is erythema multiforme or flu-like symptom after use, stop using this drug and consult the physician immediately.
5. Celecoxib is contraindicated in patients who have ever been hypersensitive to this drug and patients with history of sulfonamide hypersensitivity.
6. If the following symptoms occur during using this drug, e.g. fever, erythema multiforme, vesicle, skin lesions and other lesions appear in the mucous membranes (such as in the mouth cavity, throat, nasal cavity, sexual organs) and conjunctivitis, stop using this drug and consult the physician immediately as this may be Stevens-Johnson syndrome.
7. Celecoxib is contraindicated in patients who have had myocardial infarction or congestive heart failure (NYHA II-IV).
8. Celecoxib is contraindicated in patients who have had coronary heart disease (stenosed or occluded) or paresis, paralysis due to cerebrovascular accident.
9. Use Celecoxib with caution in patients with risk factors for developing coronary heart disease, e.g., hypertension, hyperlipidemia, diabetes, smoking, elderly, etc.
10. Use with caution in patients with hepatic and renal disorders.